ROADMAP  

Welcome to RHIZOPHARM

We take biotechnology underground: more efficient roots, smarter processes, more valuable compounds

We optimize and research synthesis systems through innovative technologies and sustainable solutions.

How do we do it?

We focus on optimizing processes for the production of secondary metabolites in roots.

This combined strategy allows us to improve the synthesis of compounds and advance the domestication of minor metabolites with high biological activity.

The Rhizosphere

A universe waiting to be discovered. A unique scientific frontier. At RHIZOPHARM, we explore the rhizosphere: a true underground biochemical laboratory.

In this interface between plant and soil, roots synthesize sophisticated allelochemicals—true molecular messengers—that regulate complex ecological interactions. These rhizospheric compounds and root exudates represent an untapped source of active ingredients with exceptional pharmacological potential.

  The next frontier of plant-based medicine lies underground.  

MISSION & VISION

Process optimization for the production of secondary and orphan metabolites.

The industrial production of bioactive compounds from roots faces specific challenges: the extreme fragility of adventitious and hairy roots, significant loss of metabolites during harvesting, and still limited knowledge about root system biology and rhizosphere dynamics.

Our mission is to transform this landscape through an integrated biotechnological approach that democratizes access to these compounds.

Through innovative technologies, we have developed sustainable solutions to amplify orphan metabolites that were previously considered inaccessible.

We have optimized synthesis systems capable of multiplying even the scarcest bioactive structures and established industrial-scale protocols that turn marginal molecules into viable therapeutic candidates.

¿Por qué elegirnos?

  Given the vast number of metabolites in plants – potentially over 1 million – and the relatively low number identified to date (less than 50,000), much of plant metabolic diversity remains uncharacterized.  

Fang, C., Fernie, A. R., & Luo, J. (2019)
Exploring the diversity of plant metabolism. Trends in Plant Science, 24(1), 83–98.

Model Species

RHIZOPHARM is currently focused on six botanical species selected for their high potential in plant improvement.

Olea Europaea (Olive)

Olea Europaea
Olive

Research focused on the bioactive compounds in the root and the study of resistance to Verticillium fungus using mutagenesis techniques.

Olea Europaea Root (Olive)
Cannabis Sativa (Hemp)

Cannabis Sativa
Hemp

Project developed in collaboration with Chulalongkorn University, focused on exploring the therapeutic potential of its roots—an area still underexplored.

Cannabis Sativa Root (Hemp)
Astragalus

Astragalus
Astragalus

A medicinal plant with widely recognized traditional use. Its limited biotechnological exploitation represents a strategic opportunity for developing new bioactives.

Astragalus Root
Withania Somnifera (Ashwagandha)

Withania Somnifera
Ashwagandha

Known for its withanolide content—compounds with adaptogenic, anti-inflammatory and antioxidant properties—this plant holds great interest in pharmaceutical development.

Withania Somnifera Root (Ashwagandha)
Pueraria Mirifica (Kwao Krua)

Pueraria Mirifica
Kwao Krua

A traditional Southeast Asian plant known for its richness in phytoestrogens. Its potential for hormonal health, aging, and regenerative medicine makes it a promising target for biotech innovation.

Pueraria Mirifica Root (Kwao Krua)
Valeriana Officinalis (Valerian)

Valeriana Officinalis
Valerian

Known for its sedative and anxiolytic effects, its root contains valepotriates and essential oils of high therapeutic value. It is an ideal model to optimize the production of neuroactive compounds using biotechnological tools.

Valeriana Officinalis Root (Valerian)

  Between Thailand and Spain

Our Team

The project is developed at two main sites: Bangkok (Thailand) and Valencia (Spain).

Management Team

Carlos Sáez

Carlos Sáez

CEO

In charge of phenotyping, plant development, and project management.

Ruslanas Andrejevas

Ruslanas Andrejevas

Financial Director

Responsible for the financial direction of the project and budget control.

Thailand Site

Chulalongkorn University (Bangkok)

Prof. Sornkanok Vimolmangkang, PhD, RPH

Dr. Sornkanok Vimolmangkang

Scientific Director

Professor at Chulalongkorn University and a leading expert in plant biotechnology. She develops innovative root cultivation systems to sustainably produce high-value bioactive compounds for herbal medicine. PhD, RPH

Kritsanapong Tawinprai

Kritsanapong Tawinprai

Cultivation Management

Graduate in Plant Production Technology with hands-on experience in hydroponic cultivation. Skilled in managing NFT and DFT systems, nutrient balancing, and environmental control. Strong background in soilless sustainable agriculture and modern cultivation techniques.

Tatiya Srichai

Tatiya Srichai

Research Assistant

Trained in in vitro cultivation and phytochemical analysis, with experience in bioactive compound research and herbal product quality assessment. Skilled in antioxidant assays, HPTLC, and controlled cannabis cultivation.

Spain Site

Valencia

Luis Torró

Luis Torró

Ingredient Development

Senior professional in health sciences with a strong background in R&D, strategic consulting, and technical management in the pharmaceutical, cosmetic, and biotechnology sectors. PhD in Pharmacy from the University of Alicante, with a track record of leading innovative projects by combining scientific insight, management skills, and regulatory expertise. Author of scientific publications on lipid metabolism, biosafety, and the effects of olive polyphenols.

Javier Simón

Javier Simón

Senior Laboratory Technician

Hands-on experience in daily plant cultivation, plant health monitoring, and basic analytics. Responsible for lab protocol compliance, supporting technical operations, and maintaining optimal growing conditions.

Facilities